Wade H. Powell

Associate Professor of Biology

Wade H. Powell joined the Kenyon faculty in 2000 following a postdoctoral appointment at the Woods Hole Oceanographic Institution. His teaching responsibilities include molecular biology and genomics, environmental toxicology, gene manipulation lab, and introduction to experimental biology. A molecular biologist and environmental toxicologist, Powell directs a research program investigating the effects of dioxin-like pollutants on the gene expression, physiology, and development of aquatic vertebrates, including amphibians, reptiles, and fish.

Areas of Expertise

Molecular Biology, Environmental Toxicology

Education

Ph.D., Emory University (1997)
M.S., East Tennessee State University (1991)
B.S., Davidson College (1987)

Selected Publications

(*Kenyon student co-authors)

*Odio, C, *SA Holzman, MS Denison, D Fraccalvieri, L Bonati, DG Franks, ME Hahn, and WH Powell (2013). Specific Ligand Binding Domain Residues Confer Low Dioxin Responsiveness to AHR1β of Xenopus laevis. Biochemistry 52(10):1746-1754.

*Iwamoto, DV , *CM Kurylo , *KM Schorling , and WH Powell (2012). Induction of Cytochrome P450 Family 1 mRNAs and Activities in a Cell Line from the Frog Xenopus laevis . Aquat. Toxicol . 114-115:165-172.

*Laub LB, Jones BD, Powell WH (2010) Responsiveness of a Xenopus laevis cell line to the aryl hydrocarbon receptor ligands 6-formylindolo[3,2-b]carbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Chem Biol Interact. 183(1):202-1.

*Anna L. Zimmermann, *Elizabeth A. King, *Emelyne Dengler, *Shana R. Scogin, and Wade H. Powell (2008) An Aryl Hydrocarbon Receptor Repressor from Xenopus laevis: Function, Expression and Role in Dioxin Responsiveness during Frog Development. Toxicol. Sci. 104:124-134.

*Lavine, J.A., *A.J. Rowatt, *T. Klimova, *A.J. Whitington , *E. Dengler , *C. Beck , and W.H. Powell (2005) Aryl Hydrocarbon Receptors in the frog Xenopus laevis: Two AHR1 paralogs exhibit low affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Toxicol. Sci. 88:62-70.

Courses Taught

BIOL 109-110 Introduction to Experimental Biology
BIOL 263 Molecular Biology and Genomics
BIOL 264 Gene Manipulation
BIOL 333 Environmental Toxicology