Introduction to Experimental Biology
See course description for BIOL 109Y.
Kathy joined the Kenyon faculty in 2000 after a post-doctoral position at Yale University analyzing the membrane targeting of G protein subunits using yeast as a model system. She is interested in many areas of biology but has a particular affinity for cell biology, molecular biology and cell signaling. In her spare time she enjoys bird-watching and attending Kenyon sporting events.
1995 — Doctor of Philosophy from Yale University
1991 — Master of Philosophy from Yale University
1989 — Bachelor of Science from SUNY Coll Geneseo, Phi Beta Kappa
See course description for BIOL 109Y.
Energy flow is a unifying principle across a range of living systems, from cells to ecosystems. With energy flow as a major theme, this course covers macromolecules, cells, respiration and photosynthesis, physiology and homeostasis, population and community interactions, and ecosystems. Throughout the course, the diversity of life is explored. The course also introduces students to the process of scientific thinking through discussion of research methodology and approaches. Majors and nonmajors may enroll. Biology majors should take this class prior to the junior year. No prerequisite. This course will be offered every year.
How is information generated, transmitted, stored, and maintained in biological systems? The endeavor to understand the flow of biological information represents a fundamental undertaking of the life sciences. This introductory course examines the mechanisms of heredity, the replication and expression of genetic information, and the function of genes in the process of evolution, with an emphasis on the tools of genetics and molecular biology to address research questions in these areas. Majors and nonmajors may enroll. Biology majors should take this class prior to the junior year. Prerequisite: BIOL 115, AP score of 5, or permission of instructor. This course will be offered every year.
Microbes inhabit the most extreme environments on earth, ranging from superheated sulfur vents on the ocean floor to alkaline soda lakes. In medicine, newly discovered bacteria and viruses cause a surprising range of diseases, including heart disease; they may even hold the key to human aging. Yet other species live symbiotically with us, keeping us healthy, and even regulate our brain. Still other microbes, such as nitrogen fixers, are essential to the entire biosphere. This course covers microbial cell structure and metabolism, genetics, nutrition, microbial communities in ecosystems, and the role of microbes in human health and disease. Prerequisite: BIOL 116.
The molecular and genomic basis of life is at the heart of modern biology. In BIOL 263, we will learn techniques and explore research questions at the forefront of molecular research, focusing on the mechanisms by which the information of the genome is expressed to form the functional molecules of living cells and organisms. The processes of DNA replication, recombination, and repair, transcription of RNA from DNA templates, and translation of RNA into protein are discussed in the context of current research, frequently using primary literature. The function of genes and the regulation and measurement of gene expression are treated in depth. Students analyze and publish interactive tutorials on the structure and function of key macromolecules. This intermediate-level course presumes a strong background in the basics of protein structure/function, central dogma processes, fundamental molecular techniques for manipulating nucleic acids and proteins, and general chemistry. Prerequisite: BIOL 116 and one year of chemistry (Intro or Honors Intro). Recommended prerequisite or corequisite: CHEM 231 and 232 (Organic Chemistry). Note: For further study of the function of proteins, membranes, and cellular processes, the complementary course BIOL 266 (Cell Biology) is recommended.
Cell signaling is the molecular choreography that allows cells to respond to changes in their internal and external environment. It is a vast and exciting field of study that underpins one of the pillars of life, the ability of organisms to sense and respond to changing conditions. This class will introduce students to the major players in signal transduction and how they coordinate to mount an effective cellular response. Examples of particular pathways will be drawn from plants, animals, and bacteria and may include quorum sensing and chemotaxis in bacteria, DNA damage response and energy homeostasis in animals, and phototropism and wound response in plants. Students will be expected to actively participate in class discussions of assigned readings, both textbook and primary literature. Prerequisite: BIOL 116, a 200-level biology course, and junior or senior standing.
Two appendix chapters and glossary for J. L. Slonczewskiand John W. Foster, January 2008, Microbiology: An Evolving Science. W. W. Norton & Co., New York.
Gillen, C.M.; Somple, M.*; Heilman, N.R.*; Watson, N.*; Blair, C.R.*; Stulberg, M.*; Thombre, R.*; Gillen, K.; Itagaki, H. The cation chloride cotransporter, masBSC, is widely distributed in Manduca sexta. Journal of Insect Physiology 52: 661-668, 2006.
Gillen KM ; Pausch M; Dohlman HG. N?terminal domain of Gpa1 (G protein alpha) subunit is sufficient for plasma membrane targeting in yeast Saccharomyces cerevisiae. Journal of Cell Science vol. 111: 3235?44, Nov 1998.